Physicians are called often to relieve people of the suffering from their disease and also to heal them. The inability of conventional medicine to adequately “heal” a number of health disorders such as chronic pain, inflammatory diseases and autoimmune diseases may have contributed, in no small measure, to the rise of non-conventional/complementary and alternative medicine (CAM). This goal of physicians can only be possible, if they initially define what a patient is. The conventional approach has been to approach disease from a physical/materialistic concept. Under this approach, all disease is a physical one. Even psychosomatic medicine basis the origin of disease in the brain. CAM – especially methods such as Acupuncture, Ayurveda, and Healing touch, amongst others, use a holistic approach, which often bases the origin of disease in the human psyche. Without the proper knowledge of what constitutes the human being proper patient care cannot be achieved. CAM therapies approach the patient from a holistic standpoint and seek to create a balance between man and his environment. The impact of the psyche/soul on the state of health of the human body and in inherited disease is being shown by epigenetics, which is demonstrating that stressors may lead to modifications in genetic function and these modifications may be modified. Evidence is mounting in conventional medicine for the value of this holistic approach, thus opening the path for a spiritualized approach to medicine. This spiritualized approach may give a broader definition for the concept of “holistic medicine”, thus, for the approach that physicians need to take to disease in the future. This might include looking at therapy not as the eradication of disease, but as the introduction of health. Through these solutions, physicians of the future may not only practice a holistic approach to medicine, but also contribute to lasting health of individuals and society. However, in order for this to happen, the physician must first recognize this scope, thus must first find the true meaning of his calling.